Aberrant CD2 expression in precursor-B acute lymphoblastic leukemia of childhood
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چکیده
منابع مشابه
JAK2 aberrations in childhood B-cell precursor acute lymphoblastic leukemia
JAK2 abnormalities may serve as target for precision medicines in pediatric B-cell precursor acute lymphoblastic leukemia (BCP-ALL). In the current study we performed a screening for JAK2 mutations and translocations, analyzed the clinical outcome and studied the efficacy of two JAK inhibitors in primary BCP-ALL cells. Importantly, we identify a number of limitations of JAK inhibitor therapy. J...
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Sir, Phenotypic subclassification within B-precursor acute lymphoblastic leukemia (ALL) has been shown to have prognostic significance in children. Common ALL antigen (CALLA) expression in Bprecursor ALL has been associated in some, but not all, studies with a favorable outcome. According to the notion that acute leukemia is a clonal expression with maturation arrest, CD34 expression on leukemi...
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ژورنال
عنوان ژورنال: American Journal of Hematology
سال: 1996
ISSN: 0361-8609,1096-8652
DOI: 10.1002/(sici)1096-8652(199607)52:3<224::aid-ajh17>3.0.co;2-f